Tshimenga,+D.

=Cri Du Chat= Research on genetic mutation =**statistics**=
 * cri du chat is a french terminology meaning cat cry it's a condition caused by a deletion occurred in the fifth chromosome by random leaving out essential genetic information, in result this not only affects the child's genotype but also phenotype children born with this condition ( 1 in 50,000 live births) have physical features that can be distinguished such as small head and jaw, wide eyes skin tags in front of eyes and excessive drooling and also experience behavioral issues such as hyperactivity, attention deficits, aggression constant tantrums and various other intellectual, mental and physical symptoms occur.this is all caused by a mistake done during synopsis** **stage in the DNA instead of the genetic information to be mixed it is completely cut off leaving the cell with less information than it should contain.It is a severe mutation leaving the chromosome physically shorter.**
 * it is reported that 90% of these cases are caused by the genetic mutation that could not be predicted.Though the chances of giving birth to a child with this condition is rare genetic mutations are not they occur more than often, where they occur and how it occur makes the difference because more than one codon can give the same protein or one letter can cause a minor change in the organism but changes that occur during crucial steps of meiosis can leave a large impact on the child in rare conditions such as this one.Also known as Chromosome 5p deletion, because it's a chromosomal mutation.it gets its original name (cat cry) it gives children a meowing like sound when they cry and one in 1 in 3 children are left without a cry by age two. 10% to 15% of the genome is lost.The children with this conditions cannot pass it on to the offspring because it's not a genetic disorder but since the individual has less genetic information the offsprings might face certain abnormalities. The ratio is 4:3 it is more common in women than men**

=**Treatment ? **=
 * Here is an image of a child with chromosome p5 deletion. His physical traits will stay with him for his whole life though they slightly change throughout the process of aging they remain distinguished from other people in their surroundings.**


 * What can parents do when they have a child with this genetic disorder, well not much it ca not be cured that is evident but parents can help by fixing so to say certain symptoms for example children with chromosome p5 have communication problems and behavioral issues parents can seek a professional in order to help them with these problems and for further and better understanding of the problem parents can seek a genetic counsellor**.

media type="youtube" key="39KmzaXJenA" width="560" height="315"
 * This is a short video to help better understand this rare condition**


 * To learn more about this rare condition here are a few links I used and would suggest for further specifics**
 * https://www.youtube.com/watch?v=39KmzaXJenA**
 * https://medlineplus.gov/ency/article/001593.htm**
 * https://www.google.ca/search?q=chromosome+deletion&espv=2&biw=1257&bih=665&source=lnms&tbm=isch&sa=X&ved=0ahUKEwjfk47xl5DRAhWd8oMKHVi_Bp0Q_AUIBigB#tbm=isch&q=chromosome+5p+deletion+syndrome&imgrc=tvJs6GXoqjkUyM%3A**
 * https://www.genome.gov/19517558/learning-about-cri-du-chat/**


 * This condition is rare and scientists still don't know the specific cause of this condition but the research is still ongoing.**

=**Evolution**= research of the evolution of Pugs

for this post my focus is on evolutionary change among pugs, though it is obvious that they have physical deformities it was not always like this theses species were once fit,sustainable to their environment until they had to go through changing mating patterns and domestic changes.Humans played a big role in this, because we chose to use this dog for show we have stripped them from their health, these dogs are dying because of an unnatural shift in their evolutionary patterns.

so what is evolution? now in order for evolution to take place there are certain factors that need to influence the specie. for example; __geographic isolation- group are separated by a physical barrier__ __behavioral isolation-group are separated by different behavior__ __temporal isolation-groups reproduce at different times.__ these are **reproductive isolation** that influence matting patterns in result expending or limiting the genetic pool of the specie. Now wolfs started begin breed by humans because of artificial selection only the ones that were calm,nice and welcoming were being allowed to have offspring in result creating a new specie which we now know as dogs. and within that specie dog were begin breaded for certain physical feature not for hunting purposes any more it had shifted into beauty reasons and that where pugs came from they were created by health deficient that are made to be look as cute but they are dangerous and limiting pugs ability to stay a live. Pug shave some may health issues in result of excessive inbreeding or incest done within the breeding here are just a few problems suffered by pugs
 * well according to the dictionary its a process by which different kinds of living organisms are thought to have developed and diversified from earlier forms during the history of the earth. **

If this specie was to be taken back to nature and depart from its domestic lifestyle it would have very low levels of survival it would be killed off by nature in a matter of years this dog and many other show dogs are a great example of reproductive isolation done by artificial selection. some of these dogs especially pugs are being inbreed to death. here's a little video to help show how many health problems a pug can have because of its so dangerously inbreed media type="youtube" key="Ez7l5Bp-GuQ" width="560" height="315"
 * Serious breathing difficulties
 * High blood pressure
 * Fainting or collapsing due to a lack of oxygen
 * Facial skin fold infections
 * Serious eye problems
 * Excessive flatulence due to excessive gulping and swallowing of air to try to overcome their breathing difficulties
 * Difficulty walking
 * Highly disrupted sleep
 * Serious eye problems
 * Excessive flatulence due to excessive gulping and swallowing of air to try to overcome their breathing difficulties
 * Difficulty walking
 * Highly disrupted sleep
 * Difficulty walking
 * Highly disrupted sleep
 * Highly disrupted sleep

To read more information about pugs, or on the evolution of dogs here's a few links to help further research:
 * https://www.rspca.org.au/campaigns/pedigree-dogs/the-pug
 * http://www.pbs.org/wgbh/evolution/library/01/5/l_015_02.html
 * https://www.youtube.com/watch?v=Ez7l5Bp-GuQ
 * http://biologos.org/common-questions/scientific-evidence/what-is-evolution
 * http://www.yourpurebredpuppy.com/reviews/pugs.html

=__**Dynamic Equilibrium**__=

their unique structures allows them to do so


====dendrites receive the information while axons are the output they send the message out.While studying the structure of the neuron i could help but wonder what happens when it goes wrong so I search it up and came across neurological disorder an abnormality in the nervous system including the central and peripheral system are effected damages to that area can cause grave problems such as psychological disorder,memory disorder and even paralysis.====

Here are a few examples of neurological disorders:

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Diseases caused by faulty genes, such as Huntington's disease and muscle distrophy

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Problems with the way the nervous system develops, such as spina disfibia

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degenerative disease, where nerve cells are damaged or die, such as Parkinson's disease and Alzheimer's disease

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Diseases of the blood vessels that supply the brain, such as stroke

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Injuries to the spinal chord and brain

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Seizure disorders, such as epilepsy

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Cancer, such as brain tumors

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here's a little video that explains neurology in its most simple but complex forms
media type="youtube" key="W4N-7AlzK7s" width="560" height="315"

=
nervous are amazing they are the reason we react to certain thing the way we do though they are small their ability to communicate is so complex and peculiar because of them our body function in coordination with our brain and action=====